A novel self-induced non-ablative three- dimensional fractional FRAC3® method for skin rejuvenation is described. The method utilizes short pulse duration/high peak power density of Nd:YAG Accelera mode laser pulses. The Accelera pulses produce a three-dimensional fractional pattern in the epidermis and dermis, with damage islands located predominantly at the sites of skin imperfections. Thermal measurements in-vivo of skin surface and in- vitro of skin cross section following the illumination with Nd:YAG Accelera pulses are presented. The measurements demonstrate the emergence of isolated »fractional« hot islands within the skin. Clinical experience following the short pulse Nd:YAG laser treatment is also presented. The FRAC3® technique offers practitioners another dimension in safety and self-regulating efficacy of non-ablative laser skin rejuvenation.