Patients and methods:
This was a single-center, randomized comparative observerblinded study comparing a 595-nm pulsed dye laser treatment and 1064-nm long pulsed Nd:YAG laser treatment in patients with angiokeratoma of Fordyce. Twenty-two patients with angiokeratoma of Fordyce were included in the present study, which was carried out within the period from July, 2013 to November 2014.
Results:
Comparisons between baseline and two months after the final treatment session by two independent dermatologists revealed clinically significant improvements in all treated areas by pulsed dye laser (61.80% ± 22.79 SD) and treated areas by Nd:YAG laser (77.63% ± 18.11 SD) where outcome was complete improvement (grade 6) in four patients on the side treated by long pulsed Nd:YAG laser and one patient only showed complete improvement on the side treated with PDL. There was a significant difference between both laser treatment with superior response with long pulsed Nd:YAG laser compared to Pulsed dye laser (p value50.05) (Table 2), which was evaluated clinically by two dermatologists according six grades of improvement (Figure 1).
