Hyaluronic acid with sorbitol – efficacy and tolerability of intra-articular treatment for osteoarthritis of the knee

In a non-interventional study under real-world conditions, 101 patients with long-standing os-teoarthritis of the knee (mean age 58 years, ca. 55% female) were treated with three intra-articular (i.a.) injections at weekly intervals of a new medication (high-dose sodium hyaluronate [hyaluronic acid] and sorbitol [GO-ON matrix]*). At the start of treatment, only 4% of the osteoarthritis pa-tients were pain-free, while 21.8% of the patients com-plained of severe or very severe pain. The proportion of pain-free patients increased steadily after each of the three injections.